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Administration Of Bone Marrow Derived Mesenchymal Stem Cells Modulate Tlr Expression During Liver Regeneration
Liver cell transplantation is a powerful alternative to orthotopic cell transplantation in the treatment of liver failures. Recently, considerable effort is being channeled to understand the nature and kinetics of directing ... -
High-throughput gene expression analysis identifies p53-dependent and -independent pathways contributing to the adrenocortical dysplasia (acd) phenotype
Sucularli, Ceren; Thomas, Peedikayil; Kocak, Hande; White, James S.; O'Connor, Bridget C.; Keegan, Catherine E. (ELSEVIER SCIENCE BV, 2018)In mammalian cells TPP1, encoded by the Acd gene, is a key component of the shelterin complex, which is required for telomere length maintenance and telomere protection. In mice, a hypomorphic mutation in Acd causes the ...